I have a Freedom Arms Field Grade .454 revolver, and it's ported. It is actually not that bad to shoot. The smooth single action grip rolls up in your hand.
My S&W .44 magnum Mountain Gun, with its light profile 4" barrel and Pachmayr "Gripper," is much more painful with heavy loads. It's nice to carry, but shooting??? When one turns loose the heavily loaded 300 grain cast "bear load" that used to be sold by Pioneer Ammo in Noxon, MT, it's obvious that something exciting has happened in one's hand!
I am interested in all of the "super mags," my catch-all name for the calibers above .44 magnum. And if post-divorce life ever again allows me signicant disposable income, I'd like a .500 S&W. But what I appreciate about the Freedom Arms .454 is that it's "normal" sized. It's not as bulky as a Super Redhawk, as huge as the X-frame Smith. It's just a "normal" single action, albeit abnormally well made and having only 5 chambers. If I had not lucked into genuine Freedom Arms leather at a show, I know the gun would fit any good standard single action holster.
For carrying, I go with the tried and true 1911 in .45 ACP, a 4" Kimber Pro Carry these days.
The only Desert Eagle I've shot was a .44 magnum. Much like the Wildey I owned, it was not bad to shoot, but had a grip ridiculously oversized for anyone with normal hands.
I like all big bangers (try an 18 lb. .50 BMG singleshot bullpup, then compare with the big Barrett 82 that's a pussycat to shoot - and my heavily handloaded Siamese Mauser .45-70 slammed me harder than either of those). But I'll go with a 1911 for a daily carry PDW, and the beautiful Freedom Arms or the handier S&W Mountain Gun for field use. For now, I'll only dream of that S&W .500 magnum and some sort of chest holster to carry it in...